After an initial golden age of promise, the medical implant industry has suffered a sharp backlash in recent years. Numerous implant systems and technologies have either failed to perform as promised or done more harm than good — some have even killed people. As recipients of these faulty devices have gone to the press or to court, the reputation of the medical implant industry has been dragged through the mud and then some.
According to the Chairman of Cardiovascular Medicine at the Cleveland Clinic, approximately 1 out of every 69 of his patients taking canagliflozin for five years will end up with a drug-related amputation. These amputation commonly involve the toe, foot, or part of the leg, and are reportedly twice as likely to occur in patients taking Invokana for several years as opposed to other diabetic drugs.